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Warning: The primary use of Topiramate, and the only use for which it has regulatory approval, is to treat seizures.Some people use Topiramate to treat other conditions, which may include PTSD, Axis II mood disorders, and eating disorders.Average total daily dose: Taken alone: 100mg daily (up to 18 years) or 100 – 200mg daily (over 18 years).Taken with other AEDs: 5 – 9mg/kg daily (up to 18 years) or 200 – 400mg daily (over 18 years). Doses per day: 2 Treatment: Used for focal seizures with or without secondary generalisation and tonic clonic seizures, where other treatment has not worked.

Add-on therapy (from 2 years): 2.5 – 4.5mg/kg twice daily up to 200mg twice daily.

However, no peer-reviewed studies have established that Topiramate is safe and effective for those conditions, and therefore these uses have not been approved by the FDA.

There is limited evidence supporting these uses that comes from small-scale case studies, but as yet there have been no large studies that researchers have published.

Also the authors noted that the long-term effects have not been studied.

Dispensing errors have been reported between Topamax (topiramate) tablets and Toprol-XL (metoprolol succinate) extended-release tablets thereby requiring extra care to ensure the correct medication is being taken.[2] People taking topiramate should be aware of the following risks: The U. Food and Drug Administration (FDA) has notified prescribers that topiramate can cause acute myopia and secondary angle closure glaucoma in a small subset of people who take topiramate regularly.

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